Chronic Pain Program

 

Across the globe, hundreds of millions are affected by chronic pain, and many suffer despite using available therapeutics.  There is a critical need for safe, non-habit forming pain medications.  With one third of Americans experiencing chronic pain (1) which impacts the quality of life of both patients and their families, there is a moral imperative to explore alternative treatment options to those currently available.

Cannabinoids have shown promise in treating a number of pain conditions including notoriously difficult to treat neuropathic pain (2) as well as inflammatory pain conditions such as arthritis (3). They act on endogenous cannabinoid receptors as well as opioid, serotonin, and glutamate signaling pathways, all of which are involved in modulating pain (4).

 

1. Institute of Medicine

2. Rahn, Hohmann. Neurotherapeutics 2009

3. Costa et al. J Pharmacol 2007.

4. Fine et al.  Rambam Maimonides Medical Journal 2013.

 

 
 
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